When you want to move the content library in ConfigMgr 2012 R2 from one drive to another, there is a great tool (ContentLibraryTransfer.exe) included in the System Center 2012 R2 Configuration Manager Toolkit. Which can be downloaded here: http://www.microsoft.com/en-us/download/details.aspx?id=36213
Syntax:
ContentLibraryTransfer.exe –SourceDrive <Current Drive Letter> -TargetDrive <New Drive Letter>
