Just recently I ran in to some trouble installing Adobe CS 5.5 Premium from the Configuration Manager Application Catalog.
From MSI logging I recieved error: CustomAction CADeploy returned actual error code 1603
But after reviewing the log files created by the Adobe installer in (64-bit) C:\Program Files (x86)\Common Files\Adobe\Installers. I found this line:
ERROR: DW046: Following Conflicting processes were running -
block:Internet Explorer (iexplore.exe)
So I closed the web-browser (Application Catalog) and the installer ran through and installed without any errors.